Tech Industry Apple Pay Mobile payments GDPR Valve 5G Virtual Reality Disney Space Star Wars Facebook Wi-Fi 0 Post a comment 5G is the real deal, a notion that grew even clearer this week as Sprint became the third US carrier to turn on its next-gen network. CNET put Sprint’s network to the test in Dallas and was impressed. Meanwhile, Apple is readying for its developers conference next week, which won’t be about splashy device unveilings so much as clues to hardware in the works.Here are some of the week’s other stories you don’t want to miss: Watch out, Apple Pay. Tap-to-pay cards are coming on strongThese cards could speed up how we shop and commute every day. Ben Fox Rubin/CNET Building a rocket in a garage to take on SpaceX and Blue OriginGilmour Space Technologies is a plucky startup in the new space race. Its first mission: sending a powerful hybrid rocket to the edge of space. Ian Knighton/CNET Disney’s Star Wars land review: Galaxy’s Edge from every angleEver wanted to visit a Star Wars planet or sit in the cockpit of the Millennium Falcon? This new Star Wars-themed land comes close to making those dreams a reality. Vanessa Hand Orellana/CNET Europe’s GDPR has accomplished a lot in its infancyAt just a year old, the General Data Protection Regulation has already forced big tech firms to make significant changes to their privacy policies. And its real effects are still to come. Saul Gravy/Getty Images The internet is changing Africa, mostly for the betterCheap smartphones are flooding Africa, giving many of its citizens access to the internet for the very first time. Andela Valve Index’s new VR controllers feel like the future of gamingThe most interesting feature in Valve’s new virtual reality system is how its controllers work in your hands. Sarah Tew/CNET Facebook quietly killed a map for discovering live videosSome users want the map back. Facebook screenshot by Andrew Hoyle/CNET First to 5G? For smartphone users, the race is kind of meaninglessEE is the first UK carrier to jump to 5G. But for most consumers, the upgrade just isn’t worth it yet.5G has arrived in the UK today. Jaromir Chalabala/EyeEm ‘First 10 years were very tough’: Aladdin star on being an Iranian actor in HollywoodIt hasn’t always been easy for Navid Negahban, but Amazon, YouTube and Netflix are changing Hollywood for the better, the Sultan says. Daniel Smith Share your voice Tags
Sunrisers Hyderabad, placed 4, will take on Mumbai Indians, placed 3, on the points table. A win for either team could well seal their spot in the playoffs, but both sides will aim for a top two finish which makes the battle an interesting affair. Delhi Capitals lost their game on Wednesday which gives Mumbai Indians a great chance to aim for the number 2 spot, and SRH, minus David Warner, will be a slightly weakened side.Predicted XI of both sides: Rohit SharmaIANSMumbai Indians: Rohit Sharma(c), Quinton de Kock(w), Suryakumar Yadav, Ishan Kishan, Krunal Pandya, Hardik Pandya, Kieron Pollard, Rahul Chahar, Beuran Hendricks, Jasprit Bumrah, Lasith MalingaSunrisers Hyderabad: Martin Guptill, Wriddhiman Saha(w), Manish Pandey, Kane Williamson(c), Vijay Shankar, Mohammad Nabi, Abhishek Sharma, Rashid Khan, Bhuvneshwar Kumar, K Khaleel Ahmed, Sandeep SharmaFantasy tips and suggestions: Kane WilliamsonIANSWicket-keeper: Quinton de Kock has been superb for Mumbai Indians at the top of the order and should once again hold the key in the powerplay overs against the SRH pace bowlers. Kane Williamson could use spinners against him and this could be his biggest threat.Batsmen: Rohit Sharma has found his groove in the last couple of matches and in this crunch match, the skipper has to play a decisive knock for this side. Also, Ishan Kishan, who might play in this match, will hold the key against the SRH spinners.For the Sunrisers, Manish Pandey has to step up and continue with his good form for his side, more so in the absence of David Warner. Also, Martin Guptill, who might replace Warner, can be picked and can be the differentiating factor in the playing XI.All-rounders: Hardik Pandya has been in blistering form for Mumbai and should once again be the key man for the hosts, more so in the death overs. Also, he has to take up more responsibility with the ball.For SRH, Mohammad Nabi can be a good pick, as he more often than not picks up wickets in the powerplay overs. Also, he can be used as a pinch-hitter in the batting order.Spinners: Imran Tahir is a definite yes. Also, young Rahul Chahar has been a revelation for Mumbai this season and should get the nod to feature in the playing XI.Seamers: Bhuvneshwar Kumar and Jasprit Bumrah – two bowlers who love bowling with each other will have to be the wicket-takers for their respective sides if they have to clinch the match and make it to the playoffs.
PM Modi won a massive mandate in the general election that ended this month after focusing his campaign on national security.ReutersPrime Minister Narendra Modi will take his oath of office on Thursday along with his ministers, though he suffered a setback at the start of his second term when key aide and finance minister Arun Jaitley opted out of the next government.The swearing-in ceremony at the forecourt of the colonial-era presidential palace Rashtrapati Bhawan will be attended by thousands of guests including Bollywood stars and leaders of neighbours including Bangladesh and Sri Lanka.PM Modi won a massive mandate in the general election that ended this month after focusing his campaign on national security, as tension with old rival Pakistan shot up over a deadly militant attack on security forces in the disputed region of Kashmir.Pakistan was not invited to the inauguration.India is proud of all those brave men and women martyred in the line of duty, PM Modi said after visiting a war memorial near parliament on Thursday. Our government will leave no stone unturned to safeguard India’s unity and integrity. National security is our priority.Many ministers who are also senior members of the ruling alliance are expected to keep their place in the government. But changes in their departments are likely, especially after Arun Jaitley wrote to PM Modi on Wednesday asking to be kept out due to health reasons.Narendra Modi and the chief of Bharatiya Janata Party (BJP), Amit Shah, could also promote many fresh faces to reward good electoral performance, mainly in the east of the country where they have traditionally been weak.Amit Shah himself is tipped to take up a role in the government, though some political analysts say he could stay on as BJP president to steer the party towards a majority in the upper house of parliament after dominating the lower house.Nearly 8,000 people, including leaders of the decimated opposition bloc, are expected to attend the ceremony that will fete the incredible rise of 68-year-old Modi, the son of a tea seller.The BJP now controls 303 of the 545 seats in the lower house of parliament, paving the way for Modi to possibly attempt controversial land and labour reforms amid concerns that Asia’s third-largest economy is faltering.This week, two major industrial bodies called on the new government to urgently take steps to bolster the economy, which grew 6.6 per cent in the three months to December — the slowest pace in five quarters.PM Modi pushed through important reforms such as a unified goods and services tax and bankruptcy law in his first five years in power but faced flak for failing to create enough jobs for millions of people seeking employment, rising farm distress and lacklustre economic growth. India’s main opposition Congress party, meanwhile, is fighting to stay relevant after being overwhelmed in two straight general elections.Its president, Rahul Gandhi, has offered to resign and on Thursday, the party said it would not send its spokespeople on television debates for a month as it analyses its latest defeat.
Following State Bank of India’s lead on Monday to sharply cut the marginal cost-based lending rate — the rate at which banks now lend to new borrowers — by 90 bps to 8 percent, rest of the PSU and private sector banks have no option but to follow suit. By Monday night itself, at least half a dozen banks announced the rate slash for different tenures. Comparison of interest rates on deposits by senior citizens after PM Modi’s speechWhile Punjab National Bank reduced the overnight lending rate by 70 basis points to 8.20 percent, Union Bank of India lowered the rates by 65-90 bps for different tenures. Similarly, Dena Bank, IDBI Bank and private sector lenders Kotak Mahindra Bank and ICICI Bank had to cut down rates.SBI announced the cut a day after Prime Minister Narendra Modi asked banks to prioritise lending to the poor and the middle class. Banks are believed to be flushed with deposits following demonetisation of old high denomination currency notes of Rs 1,000 and Rs 500.The move to cut the lending rate is expected to prompt an increase in credit offtake of banks — especially of state-run lenders — whose balance sheets are under substantial burden.However, leading brokerages are of the view that cutting lending rates of such a sheer magnitude would squeeze the net interest margins of banks and the trend may well persist for at least a few quarters. In a report on SBI, a Deutsche Bank note warned: “A 90 bps one-go rate cut is sharp and will be negative for NIMs. Though this is only for incremental loans and the immediate impact on NIMs will be gradual, but pressure will persist for at least next 4 quarters as loans reprice downwards.”A CLSA report stated that the lending rate cuts will boost credit demand in retail segments such as housing loans and any impact on margins will be mitigated as MCLR will apply only to incremental loans, as reported by the Economic Times.”A 5bps lower NIM in FY18 could impact earnings by 4%, with a higher impact on PSU banks,” said CLSA.Analysts expressed surprise at the quantum of MCLR cuts — which they primarily believe is a result of demonetisation-led excess liquidity in the banking system — and said the implication of the lending rate cut is likely to be negative for both banks as well as NBFCs, particularly catering to the housing loan segment.Shares of banks and housing finance companies, including LIC Housing Finance, HDFC, Indiabulls Housing Finance, remained under pressure on Monday in trade and may continue to underperform in the coming weeks.
Yo Yo Honey SinghYouTube ScreenshotJust 2 days since Yo Yo Honey Singh released his new track ‘Gur nalo ishq mitha’ in collaboration with Punjabi Bhangra singer Malkit Singh, the track has already struck the right chord with the audience and is trending at number 1 on YouTube. It has crossed 13 million views in hardly any time and Honey Singh fans are swooning over it, the world over!’Gur nalo ishq mitha’ is the perfect amalgamation of beats, rhythm, and bhangra, all of which are extremely popular with the audience not just in India but globally. The song is a recreation of an old Punjabi classic, which is made in Yo Yo Honey Singh style and the song is already being deemed as the next Bhangra song, guaranteed to burn the dance floors.As promised by fans before the release of the song, they have already started dancing to the tunes of the songs and making their own choreographies. The song is super colorful and gives a very cool vibe which will get you grooving on hearing it. The original song is choreographed by the very famous Bhangra crew B Funk and is definitely another chartbuster that has got the excitement soaring with its release.Creating so much excitement amongst the fans before the release of each and every song, it is all the more proof that Honey Singh is one of the most popular singers, not just among the youth but also among all the demographics.The year, 2018 has been a rocking year for Yo Yo Honey Singh as he has delivered many chartbusters namely, Dil Chori and Chote Chote Peg, This Party Is Over Now, Rangtaari to Shahid Kapoor-Kiara Advani, featuring single Urvashi Rautela. Yo Yo Honey Singh has conquered the Indian music industry with his exceptional music and inimitable style. The singing sensation has cast his magic spell all over again on the hearts of his fans and the fans are eagerly awaiting the release of his next with even 2019 being a year if hits and glitz.Yo Yo Honey Singh has many projects lined up along with his new track and with this new track coming back, the audience is even more excited for his upcoming rhythmic line-up. From movies to singles, Yo Yo’s each number goes on to be a chart buster of all times and the fans cannot wait.
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Stabilization of the doping profile by counter-ion immobilization in self-compensated doped polymer organic semiconductors. Credit: (c) Nature (2016). DOI: 10.1038/nature20133 To make optoelectronic devices a layering technique is used—a thin film conductor is caused to be in contact with a semiconductor allowing an electric charge to move between them—to facilitate the transfer an IFL is placed between them. But as Facchetti notes, conventional IFLs are considered to be inefficient—improvements would allow greater efficiency in solar cells, for example. In this new effort, the researchers suggest a particular type of polymer, part of a group called π-conjugated polymers—a type of stable polymer with high doping content that has a self-compensation mechanism that involves covalently bonded counter ions that serve to block the migration of dopants—they offer not only improved efficiency but stronger performance and more stability. But, as Facchetti also notes, most such polymers in their native state are not able to transfer large numbers of charged particles—to overcome that problem the researchers used a chemical doping process that caused the charge carriers to become denser which in turn caused the polymer to become much more conductive.To test their ideas, the researchers modified several devices (solar cells, LEDs, photodiodes, etc.), replacing conventional IFLs with ones they had created and then tested their performance. The team reports that the expected improvements in efficiency were realized, which they note, suggests such polymers have the potential to improve the efficiency of a wide variety of optoelectronic devices. More work will need to be done though before that can be proven—first it remains to be seen if such polymers can be scaled up and then it must be shown that they can stand up to the rigors of real-world demands. © 2016 Phys.org New polymer able to store energy at higher temperatures Citation: IFLs created from pi-conjugated polymers improve performance and stability of optoelectronic devices (2016, November 24) retrieved 18 August 2019 from https://phys.org/news/2016-11-ifls-pi-conjugated-polymers-stability-optoelectronic.html More information: Cindy G. Tang et al. Doped polymer semiconductors with ultrahigh and ultralow work functions for ohmic contacts, Nature (2016). DOI: 10.1038/nature20133AbstractTo make high-performance semiconductor devices, a good ohmic contact between the electrode and the semiconductor layer is required to inject the maximum current density across the contact. Achieving ohmic contacts requires electrodes with high and low work functions to inject holes and electrons respectively, where the work function is the minimum energy required to remove an electron from the Fermi level of the electrode to the vacuum level. However, it is challenging to produce electrically conducting films with sufficiently high or low work functions, especially for solution-processed semiconductor devices. Hole-doped polymer organic semiconductors are available in a limited work-function range, but hole-doped materials with ultrahigh work functions and, especially, electron-doped materials with low to ultralow work functions are not yet available. The key challenges are stabilizing the thin films against de-doping and suppressing dopant migration. Here we report a general strategy to overcome these limitations and achieve solution-processed doped films over a wide range of work functions (3.0–5.8 electronvolts), by charge-doping of conjugated polyelectrolytes and then internal ion-exchange to give self-compensated heavily doped polymers. Mobile carriers on the polymer backbone in these materials are compensated by covalently bonded counter-ions. Although our self-compensated doped polymers superficially resemble self-doped polymers, they are generated by separate charge-carrier doping and compensation steps, which enables the use of strong dopants to access extreme work functions. We demonstrate solution-processed ohmic contacts for high-performance organic light-emitting diodes, solar cells, photodiodes and transistors, including ohmic injection of both carrier types into polyfluorene—the benchmark wide-bandgap blue-light-emitting polymer organic semiconductor. We also show that metal electrodes can be transformed into highly efficient hole- and electron-injection contacts via the self-assembly of these doped polyelectrolytes. This consequently allows ambipolar field-effect transistors to be transformed into high-performance p- and n-channel transistors. Our strategy provides a method for producing ohmic contacts not only for organic semiconductors, but potentially for other advanced semiconductors as well, including perovskites, quantum dots, nanotubes and two-dimensional materials. (Phys.org)—A team of researchers from Singapore and the U.K. has found that using a particular type of polymer allowed for creating interfacial layers (IFLs) in optoelectronic devices with improved performance and stability. In their paper published in the journal Nature, the team describes their technique and their results when they made actual devices using the polymer. Antonio Facchetti with Northwestern University offers a News & Views piece on the work done by the team in the same journal issue and outlines some of the benefits of self-compensated polymers as well as some of the hurdles that will need to be overcome before they can be used in commercial products. Explore further Journal information: Nature
Categories: Lauwers News 02Jul Local lawmakers announce new road projects in St. Clair County State Reps. Dan Lauwers and Andrea LaFontaine this afternoon announced two new road projects in St. Clair County to improve the safety and efficiency of the area’s infrastructure for local motorists.Yale Road from Brown Road to the city of Yale limits will benefit from $715,000 in special grant funding to resurface asphalt, replace culverts and widen shoulders. An additional $400,000 grant will improve Gratiot Road between Pound Road and Kronner.“Lawmakers have an obligation to make Michigan’s roadways safe for our hard-working families and visitors,” said LaFontaine, R-Columbus Township. “The Gratiot Road project was identified as a priority by the St. Clair County Road Commission and will bring welcome repairs to our St. Clair community to promote safe travels.”The Legislature allocated a total of $230 million in existing funds for fiscal year 2014 to road improvements throughout Michigan. Funding grants for half of that allocation were unveiled last December.“This is another positive step taken by the Legislature to help ensure safe and efficient roads in Michigan,” said Lauwers, R-Brockway Township. “Our roads were neglected for far too long, and these small steps to bring our infrastructure back from the brink will benefit all Michigan motorists. People are telling me they don’t want to pay higher taxes at the pump, and I don’t blame them given today’s gas prices, so these incremental improvements are a great way to improve our roads.”This special funding is in addition to $258 million the Legislature approved for roads and bridges in June.Although the state has allocated almost $870 million to improve roads and bridges since fiscal year 2012, the state government spent zero general fund dollars on roads during fiscal years 2003-11.The lawmakers will continue to work on road funding solutions this summer and the fall.
Over-the-top TV specialist aioTV has integrated its video platform with the Amino Aminet A140 hybrid IPTV/OTT set-top box.AioTV enables operators worldwide to curate multiple sources of OTT video content into a TV-like experience for customers on multiple devices, including the iPad, Android tablets, PC, Mac, GoogleTV, iPhone and Android phones.“We have operating partners worldwide that are looking to add aioTV OTT services to the TV,” said Mike Earle, founder of aioTV Inc. “The Amino A140 are fantastic enabling set-top boxes for our OTT video platform.”
The DVB is exhibiting at IBC on stand 1.D81 The DVB will use its presence at IBC to demonstrate HEVC-encoded content in multiple UHD services utilising DVB-S2X and multiple HD services via DVB-T2.Following the approval in July of the specifications for the use of HEVC in the DVB environment and DVB-UHDTV Phase1, which was seen as a significant step in the road to Ultra High Definition TV services, at this year’s IBC, DVB’s main concentration will be to demonstrate how the coding efficiency of HEVC can be used to increase the capacity of the DVB-T2 terrestrial platform as well as for the new DVB-S2X satellite standard.Utilising HEVC encoding, multiple UHD services will be delivered using DVB-S2X and multiple HD channels over DVB-T2. The DVB-S2X demonstration will highlight the new standard that offers spectral efficiency of up to 50% for professional applications. S2X will be implemented with HEVC to deliver 4 UHD signals at a data rate of 100 Mbps. DVB-S2X provides more choices for roll-off factors as well as additional modulation and Forward Error Correction options that allow for the more efficient use of satellite transmission channels, according to DVB. It enables channel bonding of up to three satellite channels, which support higher aggregate data rates and allow for additional statistical multiplexing gain for services such as UHDTV.In another demonstration up to seven HEVC encoded HD channels will be delivered in one multiplex using DVB-T2 in a robust mode suitable for small indoor antennas and portable reception. Both fixed reception and mobile reception will be demonstrated.
Vivendi has stated that it “cannot on a long term basis continue to finance the losses of Canal+ channels in France” following four years of losses. Posting its financial results for 2015, Vivendi said that the pay TV outfit posted negative EBITA of €264 million last year, an increase in its losses of €76 million year-on-year.Vivendi said that “this situation threatens the entire Canal+ Group, which employs 8,200 people and is a major player in the financing and development of the movie industry”, in which it invests “close to €800 million” in France and internationally.The media giant said that it has set making the group break even by 2018 a priority for its new management team, which will involve increasing investment in original content and premium contente and improving the user experience. It added that this would be done in an “essential cost-efficient manner”.Vivendi said that it had already invested €1.5 billion in Canal+ and that its investments would remain substantial in the medium term.As part of the drive to stem losses at the pay TV group, Canal+ has confirmed an exclusive distribution deal with rival pay TV outfit beIN Sports, whereby it will become the exclusive distributor of beIN Sports channels in France for the next five years (see separate story).Canal+ posted revenues of €5.51 billion, up 1.1% or 0.2% at constant currency, for the year. Revenue from its French pay TV operation was down 2.1%, while international pay TV revenues were up 7.2%. Operating income was €542 million, down from €618 million.The group had 15.7 million subscriptions globally at the end of 2.15, up 400,000 year-on-year, driven by international sales. Individual subscribers numbered 11.2 million, driven by its performance in Africa. Vivendi said that Canal+ now had over two million subscribers across 30 African countries. The group added 25 channels to its offering in Africa last year, following the launch of flagship African entertainment channel A+ in October 2014.Separately, Vivendi said its acquisition of a 26.2% stake in Banijay Zodiak, the new enlarged production company arising from the combination of Banijay Group and Zodiak Media, would be finalised shortly.Vivendi’s production outfit Studiocanal posted a 5.7% incrase in revenues, or 2.3% at constant currency, thanks to the sale of film rights of titles including Paddington, Imitation Game and Shaun the SheepVivendi has also announced a public tender offer for the shares of French video games company Gameloft that it does not already own. Vivendi, which passed the 30% threshold of ownership of Gameloft that triggered the move, is offering €6 a share for the company, a premium of 50.4% on its share price before Vivendi’s initially entry in October last year. Gameloft’s management remain strongly opposed to the offer.Vivendi posted revenues of €10.76 billion for the year, up 6.7% or 1.4% at constant currency, with the difference in part due to a positive impact of the appreciation of the dollar and the pound on Universal Music Group’s results.Vivendi’s operating income declined by 4.3% to €1.11 billion, thanks to Canal+’s losses and losses from new initiatives, partly offset by the improved performance of OTT service Watchever, which reached breakeven following the implementation of a transformation plan in the second half of 2014.
THREE wards at Altnagelvin Hospital have been closed to admissions because of a vomiting bug.Wards 3, 41 and 42 are not taking new patients because of the norovirus.A small number of patients in the hospital were affected. ShareTweet The Trust said in a statement: “Ward 41 (Acute Medical Unit) at Altnagelvin Hospital remains closed to admissions as a result of an outbreak of Norovirus (known as the vomiting bug). “Ward 42 (Acute Elderly Medicine) and Ward 3 ( Respiratory) are also now temporarily closed to admissions as of this afternoon. This is also due to a vomiting bug. “The Trust’s Infection Prevention and Control team is continuing to provide advice to staff and increased infection control measures have been put in place in these wards.“Those who are visiting the hospital are asked to: – Thoroughly wash their hands before and after visiting;– Visitors should visit only one patient whilst at the hospital;– Refrain from sitting on hospital beds– Do not move from ward to ward when visiting.People should also avoid visiting the hospital if they are feeling unwell.The situation is being reviewed daily.Vomiting bug outbreak closes three wards at Altnagelvin hospital was last modified: June 13th, 2018 by John2John2 Tags: healthNOROVIRUSVomiting bug outbreak closes three wards at Altnagelvin hospitalWESTERN TRUST
Total payments for health care, long-term care, and hospice for people with Alzheimer’s and other types of dementia are projected to increase from $203 billion in 2013 to $1.2 trillion in 2050. (Source: Alzheimer’s Association, 2012 Alzheimer’s Disease Facts and Figures, Alzheimer’s & Dementia, Volume 8, Issue 2.) Right now, about 5.2 million Americans suffer from Alzheimer’s—already a large number—but in just 26 years that number will have more than doubled, to 11 million. Here’s just a glimpse at the monstrous healthcare costs we’re facing: In 2013, the direct costs of caring for those with Alzheimer’s to American society totaled an estimated $203 billion, of which $142 billion came from taxpayers through Medicare and Medicaid. It’s hardly a state secret that we Americans are getting old. Both in raw numbers and as a percentage of the overall population, the 65+ cohort is growing rapidly as the baby boomers slide into retirement. On the plus side, these data confirm that more Americans are living to a ripe old age than ever before—many of them in good health well into their seventies and eighties. But all too often, with age comes susceptibility to ever more serious ailments and a diminishing quality of life—especially if you contract a disease that obliterates your innate sense of self and destroys everything that makes life worth living. That’s what Alzheimer’s disease does. This most common type of dementia was first described by the German physician Dr. Alois Alzheimer more than a century ago… but to this day science isn’t sure what exactly it is and what causes it. It is also increasing in incidence, as would be expected with an aging population: This dramatic rise includes a 500% increase in combined Medicare and Medicaid spending. It’s a serious healthcare crisis in the making—significant today, and on its way to astronomical levels in short order—putting an ever greater amount of stress on a medical establishment that is already coming apart at the seams. What About a Cure? As I’ve mentioned before, despite decades of research, until recently scientists knew precious little about the specifics and causes of Alzheimer’s. Their best guess was that it involved a combination of genetic, environmental, and lifestyle factors. But there was no reliable biomarker that would help indicate who would be affected, let alone a sure pathway to a treatment. The best the pharmaceutical industry managed to come up with were treatments that slowed down, rather than stopped, the progression of the disease—and even then only for a short period of time. In fact, to this day there are just five FDA-approved drugs to treat Alzheimer’s at all, and none is particularly effective. According to a stark appraisal from Consumer Reports Health, “When compared to a placebo, most people who take one will not experience a meaningful benefit.” The Alzheimer’s Association reports that on average, the five approved AD drugs show some efficacy for only about six to twelve months, but only in approximately half of the individuals who take them. Nevertheless, despite their lack of efficacy, these drugs posted some impressive sales figures before cheaper generics became available. A real breakthrough in the treatment of Alzheimer’s, the scientific world agrees, would be a game-changer for modern medicine. And that breakthrough may just be on the way. Right now, there’s a small company that looks like it may beat its competitors to the finish line. Metallic Catalysts Alzheimer’s disease diminishes the ability of neurons in the brain to communicate with one another. That ultimately leads to neuronal death and, over time, destroys memory and thinking skills. Although scientists have yet to pinpoint a single cause for the disease, they’re getting far closer to understanding the disease than ever before. Beta-amyloid plaques, for example—the infamous “plaques” that form in the brain as part of the disease’s development—show links with chronic and persistent infections, such as gingivitis. Also, the interaction of these amyloid plaques and biological metals (zinc, iron, copper, etc.) seems to result in deterioration of brain cells. It was once thought that beta-amyloid plaques were the primary cause of the damage to neurons seen in AD, because they’re the most visible when the brain of a deceased AD patient is dissected. But now a growing number of researchers believe that the small, still-soluble beta-amyloid oligomers may be the main culprits because they’re often found in the spaces between neurons (synapses), where they are believed to disrupt communication by interacting with the metals and creating a short circuit. With nothing firing across the synapses, information is no longer transmitted from one neuron to another, and the cells start to die off from lack of use. One small biotech startup has been moving forward with the development of compounds to render these biological metals inactive, preventing this short circuit and allowing the brain to resume normal function or even heal. Today, that company sits on the cusp of what may prove to be the single most important data readout on the subject since its inception—a trial that should prove whether this technique shows as much efficacy in a large group of human patients as it has shown in animal testing and in anecdotal evidence from early human trials. In the months since we started following this small company, many investors have caught on to its potential. Once a tiny company with a $30 million market cap, news of its successes, including positive readouts from a study of the much smaller but related Huntington’s disease, have driven the stock up nearly 400% in the last year. While that might sound like much of the good news has been priced in, we beg to differ. Global investment firm Deutsche Bank, for instance, recently pegged the global Alzheimer’s drug market at $20 billion per year. With no real competition in the market, the company could easily capture 20% of that market—or about $4 billion annually. Even if this small company can only realize a quarter of that revenue after working through big pharmaceutical partners to manufacture and distribute the treatment, it could see $1 billion in annual revenues. If we compare this company to other companies with similar revenues in the same industry, it means that in the long run, its shares could be worth 10x what they trade at today, even after the recent run-up—and that’s with many very conservative assumptions along the way. A real breakthrough treatment could make these numbers seem ridiculously small. But you won’t have to wait that long to make money. Positive trial results, which are due in March, could easily double the share price as the company moves steadily closer to market. Of course, there aren’t any guarantees, but the company doesn’t even have to provide groundbreaking news at this point. If early trial results can simply be repeated, the potential is enormous. If you want to get into this exciting biotech play before the next big news is due out, try Casey Extraordinary Technology risk-free for 3 months. If in that time you haven’t made any money from our picks or aren’t satisfied for whatever reason, just call or email us and cancel for a full refund of every penny you paid. That way, you don’t have to miss out on this potential windfall that could happen just weeks from now. Click here for more details on this amazing Alzheimer’s breakthrough, or go directly to the order form to get started.
First Russia, and now China. US politicians aren’t doing themselves any favors getting involved in foreign disputes, especially with their track record of failed foreign policy. “Hong Kong affairs fall entirely within China’s internal affairs,” Chinese Embassy spokesman Geng Shuang states. “We hope that some countries and people can be prudent in their words and deeds, refrain from interfering in the internal affairs of Hong Kong in any way, do not support the illegal activities such as the ‘Occupy Central,’ and do not send any wrong signals.” Don’t make any mistake about this official statement: this was China’s way of telling the US politicians to zip it and mind their own business. How did all this start? With US Senator Menendez. New Jersey Democrat Bob Menendez sent a letter to Hong Kong’s Chief Executive Leung Chun-ying asking that he respect the rights of his people (Hong Kong citizens), and condemning the Hong Kong government’s “excessive” use of tear gas under his watch. Tomorrow, US Secretary of State John Kerry meets with Chinese Foreign Minister Wang Yi. With China already having passed along its “butt out” message to the US, it will be interesting to see if Kerry tries to push his country’s misguided agenda, and if the mainstream media pick up on any of it. But what does this all mean? It means the US is being firmly put in its place by the emerging superpowers in the world. First it was President Putin standing up to Obama over Syria in 2013. Then again in early 2014, Putin stood up to the US sanctions. Now China has sent a sharp official message to the US, warning it to stop meddling. It’s hardly a new US tactic to foment dissent in a foreign state. We saw it in the support of anti-Assad rebels in Syria. We saw it again in Ukraine, where the US financed the February coup. With China, Washington will have to resort to words rather than guns, but it would love to see the people rise up against communism. Last Monday, White House spokesman Josh Earnest made that clear when he stated, “The United States supports universal suffrage in Hong Kong in accordance with the Basic Law and we support the aspirations of the Hong Kong people. We have consistently made our position known to Beijing and will continue to do so.” Earnest is just the messenger, of course. That message comes directly from Obama’s Oval Office. China is no backwater nation. It’s a global economic giant. It will stand up to the US on this issue, and not just because of how much it resents outside agitators. The more important reason is that the last thing the government of China needs is a wave of democratic protests across the nation. Remember, China has more than 160 cities with a population over 1 million. Vancouver, BC, Canada, the epicenter of the junior resource sector, doesn’t even have 1 million people (the greater Vancouver region does, but the city core doesn’t even have 750,000 inhabitants). For further perspective, consider that all of Europe only has 35 cities with 1 million people or more. China now has over 160 such cities, and it’s projected that by 2025—just 11 years away—that number will jump almost 40%, to 220! If a wave of protests were to spread across any large percentage of those 160 cities, that would be a disaster for the Chinese economy. And the worse the economy got in China, the worse the protests would become. Things could spiral out of control very quickly, and the government and military would have some serious problems on their hands. Given the dangers, it’s easy to understand why the Chinese government would go to great lengths to suppress any widespread protests. The last thing the government wants is another incident like Tiananmen Square, where hundreds of students were massacred by the authorities in June of 1989. We must bear in mind that what goes on in China may seem mysterious to an outsider who’s been raised on the notion that all the world’s people crave democracy. But for the majority of the Chinese, what they’ve grown up with is completely normal to them. What the governmental authorities feel they need to do to keep order may be repellent to Americans, but that’s their normal. So… how does what happens in China affect you? If you’re an investor, work in the resource sector, and/or have a job that’s involved in international finance, pay attention. All resource investors must realize that whatever happens in China will affect commodities around the world, for good or ill. Napoleon was quoted as saying, “China is a sleeping giant. Let her sleep, for when she wakes she will move the world.” He was right. China is awake, and it has more than shaken the world. There isn’t a better quote to summarize the importance of China today in the resource markets. Whether you’re talking coal, oil, iron ore, or copper, China matters. Take oil, for instance. In the month of September 2014, the US imported an average of 7.47 million barrels of oil a day. Ten years ago, the US imported an average of 9.73 million barrels a day in the month of September. These are data from the US’s Energy Information Administration website. (By the way, we’ve seen many reports from misinformed reporters claiming that the US imports only 5 million barrels of crude oil a day now. That is incorrect information, as the government data show.) How much oil does China import? A little over 6 million barrels of crude per day. China is the world’s second-largest oil importer after the US, which it is expected to pass in 2015. China also has the second-largest refining capacity of nearly 14 million barrels of oil a day, trailing only the US’s total of just under 18 million barrels. Again, China is projected to forge ahead in 2015. This is just one of the many ways in which China matters. So how do we profit from the information we have? History shows that energy stocks move in cycles. We’ve now completed a major analysis of the best oil producers in North America; we believe they’re on the cusp of a tremendous boom. The only way to position your portfolio for a major upswing in the oil sector is to buy before the boom is in full swing—and that is now in my opinion. Readers who want to understand, hedge against, and even profit from the decline of the petrodollar are advised to sign up for my Casey Energy Report. For most readers, this is literally a once-in-a-lifetime opportunity. Test my newsletter for the next 3 months, and if you don’t like it or don’t make any money, just cancel within that time for a full and prompt refund. Upon signing up, you’ll receive the September issue of the Casey Energy Report, which will provide you with an in-depth analysis of my favorite companies, including dividend-paying and small-cap companies ready to profit from the Russia/US confrontation that I’ve termed “the Colder War.” So if you want to get behind the real winners in the European Energy Renaissance and the Colder War and make some serious money from the inevitable bull market in oil, click here to get started now.
We all hear this advice with set-your-clock regularity: “Follow the smart money.” But who or what is this so-called smart money? Why is it smart? How do we find it—let alone try to determine where it’s headed? And how can we take advantage of it? Taking it from the top, what is “smart money”? It’s money put into companies by the top tier of experienced investors, hedge fund managers, and/or institutions. The opposite of it is “dumb money”—the cash that pours in once the investment gets touted front and center in the financial press as “the latest hot secret” for the naïve millions to read—commonly followed by the investing herd stampeding into the sector and driving prices up into a bubble that bursts and leaves heavy losses in its wake. Obviously we want to follow the smart money and avoid getting swept away with the dumb money. But what makes the smart money smart? It’s simple, really. 1. Those in the know have better access to information—and access to better information. If your job were to find the best investments and manage millions, perhaps billions, of dollars, wouldn’t you try to take every advantage the law allows (and maybe even exploit some of the legal gray areas)? This could mean gaining access to policymakers, personally getting to know company management and technical experts, or just immersing yourself in how the market is moving and why. Honestly put, the smart money may know important news hours or even days before it hits the newswires, due to a level of access unavailable to the average retail investor. Using this information, the smart money is able to make better-informed decisions, and make them faster. Sticking with the buy low/sell high mantra is easier when you’re in that position. 2. Serially successful people tend to continue to be successful. The Pareto Principle posits that 80% of an event’s effects often arise from 20% of its causes—or in financial terms, 20% of the people working in a given sector generate 80% of the wins. Being a math guy, I’ll take it one step further. If the top 20% of that group again generates roughly 80% of the wins, this means the top 4% of entrepreneurs generate 64% of the wins. Those who have previously demonstrated that they have what it takes are the ones most likely to do it again. I call it the “4-64” rule. Pay attention to what these folks are doing. 3. They don’t allow the herd to trample them. When you hear about the latest investment fad in the news, you can be pretty sure that idea has passed through hundreds of thousands of hands on its way to you. By the time it hits the airwaves, it’s usually too late: The real money, based on the company’s real value, has already been made. Herd investing is one of the most dangerous threats to your net worth. As the dumb money flows in and the share price begins to climb, it’s easy to get complacent and think that the shares will keep going higher. But that’s when the smart money strikes, pulling out their investment at the expense of the dumb money, taking its profits and leaving the field. Sooner or later, the price takes a nosedive under the selling pressure. It’s the herd that always ends up holding the bag. How to take advantage? Well, let’s take Warren Buffett for example. I have no hesitation labeling him and his group of companies and funds as very smart money. It’s also no secret that Buffett has a cult following, and after it becomes public that he owns a stock, that the “not so smart” money rushes in and pushes that stock even higher. So, the ideal is to get into an investment before the smart money… or at least at the same time. Then, when the involvement of someone like Warren Buffett gets noticed, the herd will drive the price upward, and you will reap the rewards. Of course, you also want to get out before the inevitable decline arrives, which may mean you exit a little early. No problem. You want to preserve your winnings, and no one ever lost money by taking profits. The nice thing is, if it’s basically a sound company, you can ride this cycle multiple times. That’s exactly what we did with ExxonMobil. We got in low, booked our gains, and moved on. It’s now pulled back enough once again that we saw another good entry point, and we jumped back into the stock. But what about our final question? How do you figure out where the smart money is headed next, so that you can get in with or—better yet—just ahead of them? Answer: you do a lot of hard work. There are no shortcuts. You have to ferret out the small number of solid companies that are selling at a discount—and discard all the rest. History is also your guide. It shows that energy stocks move in cycles. We’re somewhere in the trough of a long down cycle, which is exactly the time to go bargain hunting. To maximize our chances of finding the most compelling buys, we’ve now completed a major analysis of the best oil producers and service companies in North America. We’ve locked in our gains before the market selloff on many of the producers, and we believe now is the time to start buying and start building your position in the right companies, during market pullbacks and market weakness. Oil has dropped $15 per barrel in the last year, and majors are sale. Fortune favors the bold, and the key to buying is to do so when others are fearful. This is as true in the oil sector as any other. Buy before the smart money becomes comfortable to stake out major positions. Way before the herd takes notice. And that time is now, in my opinion. Readers who want to make money as the energy sector turns higher—and who want to understand, hedge against, and even profit from the ensuing decline of the petrodollar—are advised to sign up for my Casey Energy Report. For most readers, this is literally a once-in-a-lifetime opportunity. Test my newsletter for the next 3 months, and if you don’t like it or don’t make any money, just cancel within that time for a full and prompt refund. Upon signing up, you’ll receive the September issue of the Casey Energy Report, which will provide you with an in-depth analysis of my favorite companies, including dividend-paying and small-cap companies ready to profit from the Russia/US confrontation that I’ve termed “the Colder War.” So if you want to get behind the real winners, be a part of the “smarter money,” and book some serious profits from the inevitable coming bull market in oil, click here to get started now.
Ethnicity: White and Asian women have the highest risk of osteoporosis, while African American and Hispanic women have a lower risk. Weight-bearing exercise can help keep bones strong and prevent or slow osteoporosis progression. Credit: Shutterstock Nutrition: Eating a diet that’s low in calcium and vitamin D increases osteoporosis risk. This article is for informational purposes only and is not meant to offer medical advice. Being a couch potato: Not getting enough physical activity or too much bed rest following an injury, illness or surgery weakens bones over time. Osteoporosis risk factors The following factors can increase a person’s risk of developing osteoporosis, according to the Cleveland Clinic. Age: Bones typically become thinner and weaker with age. Osteoporosis treatment and medications People with advanced osteopenia as well as those with osteoporosis need medication to reduce their risk of fractures. Bisphosphonates are usually the first drugs used to treat osteoporosis, but while they help slow bone loss, they don’t help build new bone. These drugs include alendronate (Fosamax), risedronate (Actonel) and ibandronate (Boniva). Studies have shown that alendronate can reduce the risk of spine and hip fractures by up to 50%, Rosen said. Once a person has started treatment for osteoporosis, bone-density testing should be repeated every two to three years to monitor how the density is changing and whether treatment is working, Rosen said. For severe osteoporosis, patients may need one of three medications given by injection that actually build new bone, Rosen said. These include teriparatide (Forteo), abaloparatide (Tymlos) and romosozumab (Evenity). But after a year on these bone-building drugs, a patient needs to take bisphosphonates; otherwise, all the bone-density gains will be lost, Rosen said. In addition to medication, people with osteoporosis should aim to include 1,200 milligrams of calcium a day in their diet, from food or supplements (preferably calcium citrate), Rosen said. He also recommends taking 1,500 to 2,000 International Units (IU) of supplemental vitamin D each day. Being physically active is also beneficial for people with osteoporosis. Rosen recommends regular workouts that include weight-bearing aerobic activity, as well as strength training, balance and posture exercises. Additional resources: Consuming adequate amounts of foods rich in calcium and vitamin D throughout life. Osteoporosis is a common disease that makes bones weak, thin, brittle and more likely to break. The condition typically occurs in women after menopause and can increase the risk of fractures, especially in the hip, spine and wrist, according to the National Institutes of Health. The condition is often called a “silent disease” because bone loss can happen slowly and without any warning signs. People may not be aware they have osteoporosis until they break a bone, lose height or develop hunched posture. About 10 million Americans have osteoporosis, and another 44 million have low bone mass, or osteopenia, placing them at increased risk for osteoporosis, according to the National Osteoporosis Foundation. There are a number of factors that may lead to osteoporosis, said Dr. Harold Rosen, an endocrinologist and director of the Osteoporosis Prevention and Treatment Center at Beth Israel Deaconess Medical Center in Boston. One such factor is the accelerated bone loss that occurs after menopause, he said. Men also lose bone as they age, normally once they’re in their 60s and 70s, Rosen said. Some men think osteoporosis affects only women, but it strikes men too, he explained. Low calcium intake and low vitamin D levels in the body can also lead to bone loss, Rosen told Live Science. The body needs a good supply of calcium and other minerals to form bone, and vitamin D helps absorb calcium from food and incorporate the nutrient into bone. In addition, unhealthy habits, such as smoking and excessive drinking, can speed up bone loss, he said. Bone Density Decreases in SpaceBone loss is a serious issue that has plagued astronauts since the dawn of the Space age. In the microgravity environment bones are remodeled with a decrease in mineral density. Good nutrition, increased vitamin D intake and exercise are used to battle the issue aboard the ISS.Volume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Better Bug Sprays?01:33关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.livescience.com/65900-osteoporosis.html?jwsource=cl已复制直播00:0002:4102:41Your Recommended Playlist01:33Better Bug Sprays?01:08Why Do French Fries Taste So Bad When They’re Cold?04:24Sperm Whale Befriends Underwater Robot00:29Robot Jumps Like a Grasshopper, Rolls Like a Ball02:31Surgical Robotics00:29Video – Giggly Robot关闭 Family history: People whose parents had a hip fracture may be more likely to develop the disease. Osteoporosis symptoms and diagnosis Osteoporosis may cause no symptoms in its early stages, and as a result, the disease can go unnoticed for decades. Some visible signs of osteoporosis may be a loss of height and a curve in the upper back, which may cause stooped posture. A “dowager’s hump” may occur when several vertebrae collapse from osteoporotic fractures in the spine. Other symptoms may include back pain, from a fracture or a collapsed vertebra in the spine, or tooth loss, if osteoporosis has affected the jawbone. Hip fracture is another serious consequence of osteoporosis. About 20% of older adults who fracture a hip die within one year from complications of the broken bone or the surgery needed to repair it, according to the National Osteoporosis Foundation. Doctors may perform a bone mineral density (BMD) test to determine if a patient has osteoporosis, according to the Mayo Clinic. The test uses a special X-ray machine to measure the mineral content at three different bone sites, typically the hip, the spine and the top of the femur. The scan can reveal if a person has low bone mass at any of these three bone sites by comparing the patient’s bone density to the normal bone density in a healthy 30-year-old person of the same sex. BMD testing is recommended for women who are 65 or older and for women 50 to 64 who have certain risk factors for the disease. Men over the age of 70 or younger men with risk factors should also be screened for osteoporosis. Review this list of calcium-rich foods from the University of California, San Francisco Medical Center. Medical problems: Numerous health conditions and diseases can also increase a person’s risk for osteoporosis. Maintaining a healthy lifestyle, such as avoiding smoking and limiting alcohol consumption, reduces bone loss. Getting regular weight-bearing exercise. How bone changes over time The body is continually breaking down small areas of old bone tissue, a process called bone resorption, and replacing that old tissue with new bone tissue. During childhood and adolescence, new bone is deposited faster than old bone is removed. This makes bones larger, heavier and denser. Peak bone mass, or when bones reach their maximum density and strength, typically occurs around age 30 for both sexes. Around age 35, bone breakdown occurs faster than the replacement by new bone, causing a gradual loss of bone mass, according to the National Institute on Aging. Women undergo more-rapid bone loss in the first few years after menopause (around age 51) than in their 30s and 40s because the ovaries produce much less estrogen, a hormone that protects against bone loss, according to The American College of Obstetricians and Gynecologists. Men in their 50s and 60s also start to lose bone mass, but at a slower rate than women do. It’s not until ages 65 to 70 that men and women begin losing bone mass at about the same rate. For that reason, osteoporosis is more common in women. The condition affects about 25% of women and 5% of men ages 65 and over, according to the Centers for Disease Control and Prevention. Can osteoporosis be prevented? The more bone a person builds early in life, the better that individual can resist bone loss later on. Prevention should start when people are younger, during their peak bone-building years, with the following steps, according to the National Osteoporosis Foundation: Body size: Petite and thin people are at greater risk of this condition because they have less bone to lose than people with larger frames and more body weight. Download a helpful brochure from Osteoporosis Canada on managing osteoporosis through exercise. Sex: Women are more likely to develop osteoporosis than men, because women have less bone tissue and lose bone faster after menopause. Learn more about osteoporosis in men from the National Institutes of Health. Unhealthy habits: Smoking and consuming too much alcohol can both increase bone loss. Osteoporosis bones are porous and weak compared to healthy bones that are more dense. Credit: Shutterstock Medications: Using certain drugs on a long-term basis can lead to bone loss. These medicines include corticosteroids, such as prednisone; heparin, a blood thinner; selective serotonin reuptake inhibitors (SSRIs), a class of antidepressants; and aromatase inhibitors, used to treat breast cancer.